What is Vitiligo Possible treatment with Protopic Tacrolimus
Created by my guide what is vitiligo possible treatment with pro topic tacrolimus vitiligo is a long-term skin condition characterized by patches of the skin losing their pigment the patches of skin affected become white and usually have sharp margins the hair from the skin may also become white the inside of the mouth and nose may also be involved typically both
Sides of the body are affected often the patches begin on areas of skin that are exposed to the sun it is more noticeable in people with dark skin vitiligo may result in psychological stress and those affected may be stigmatized the exact cause of vitiligo is unknown it is believed to be due to genetic susceptibility that is triggered by an environmental factor
Such that an autoimmune disease occurs this results in the destruction of skin pigment cells risk factors include a family history of the condition or other autoimmune diseases such as hyperthyroidism alopecia areata and pernicious anemia it is not contagious vitiligo is classified into two main types segmental and non segmental most cases are non said mental
Meaning they affect both sides and in these cases the affected area of the skin typically expands with time about 10% of cases are said mental meaning they mostly involve one side of the body and in these cases the affected area of the skin typically does not expand with time diagnosis can be confirmed by tissue biopsy tackle imus sold under brand name pro topic
In usa also known as fume ison or fk506 is an immunosuppressive drug used mainly after allogeneic organ transplant to lower the risk of organ rejection it achieves this by inhibiting calcineurin involved in the production of interleukin 2 a molecule that promotes the development and proliferation of t-cells which are vital to the bodies learn an immune response
Tacrolimus is also used in the treatment of other t-cell mediated diseases such as eczema and psoriasis severe refractory uveitis after bone-marrow transplants exacerbations of minimal change disease kimora’s disease and the skin condition vitiligo he effectiveness of tacrolimus in treating vitiligo as in other skin disorders may stem from its suppression of
Auto antibody recognition of cell surface melanocyte antigens and inhibition of subsequent cytotoxic t lymphocyte reactions there is no known cure for vitiligo for those with light skin sunscreen and makeup are all that is typically recommended other treatment options may include steroid creams or photo therapy to darken the light patches alternatively efforts
To lighten the unaffected skin such as with hydroquinone may be tried several surgical options are available for those who do not improve with other measures a combination of treatments generally has better outcomes counseling to provide emotional support may be useful globally about 1% of people are affected by vitiligo in some populations it effects as many
As two 3% males and females are equally affected about half show the disorder before age 20 and most develop it before age 40 vitiligo has been described since ancient history thank you for watching this video
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What is Vitiligo Possible treatment with Protopic Tacrolimus By Kimavi