This animated video is designed for patients with type 2 diabetes. It describes how glucagon-like peptide-1 (GLP-1) receptor medicines work in the body to manage blood glucose levels and explores key features of these medicines, such as dosing, how to take them, and safety information.
In type 2 diabetes the body does not make enough of the hormone insulin or it isn’t being used correctly leading to a buildup of sugar or blood glucose in the body type 2 diabetes can worsen over time requiring several medications to manage blood glucose levels one type of treatment called glp-1 receptor agonists or glp-1 medicines is similar to the hormone
Glp1 that occurs naturally in your body these medications help your body release more insulin when needed slow digestion so that food leaves the stomach more slowly which helps manage blood glucose levels after a meal and tell your brain that you’re no longer hungry although all glp-1 medicines work in similar ways there are differences in how long they work or
Act in your body which affects how often you take them this ranges from twice daily to once daily to once weekly glp-1 medicines are available as injectable pens or as a tablet taken by mouth short-acting injectable glp-1 medicines include twice-daily baeta and once daily ad-lixin short-acting medications are typically taken before a meal or first thing in the
Morning tend to have a greater effect on after-meal glucose levels and have less of an effect on fasting glucose levels long-acting injectable glp-1 medicines include once daily victoza and once weekly medicines trulicity an extended release version of baeta called by durian and osempec these can be taken any time of day but once daily medicines should be taken
Around the same time each day and once weekly medicines should be taken on the same day each week long-acting glp-1 medicines have greater effects on overnight and fasting glucose levels and hba1c levels most injectable glp-1 medicines are started at a low dose and then increased if needed they must be injected into the fat layer just under the skin such as in
The stomach area or abdomen outer thighs upper buttocks hips lower back and backs of the arms follow all instructions in the medication package insert and ask your health care provider to show you how to give yourself an injection once daily robelsus is now available for adults with type 2 diabetes it is the first glp-1 medication that can be taken by mouth like
Injectable glp-1 medicines it has the same effects on blood glucose levels and hba1c dosing starts at 3 milligrams for 30 days and then increases to 7 milligrams a 14 milligram dose is also available this medication should be taken on an empty stomach after waking up in the morning and with no more than four ounces of water it must be swallowed whole and should
Not be crushed or chewed also you should wait 30 minutes before eating drinking or taking other medications once daily robelsus works best if you eat 30 to 60 minutes after taking it follow all instructions in the medication package insert adding a glp-1 medicine to your treatment plan may be helpful these medications can help you reach your target hba1c because
They can lower levels by up to 1.6 percent note that hba1c goals vary for each person so check with your healthcare provider about your goals they can also prevent or reduce how often insulin related low blood glucose or hypoglycemia and after meal hypoglycemia occurs protect people with heart disease from heart attack or stroke and slow the worsening of kidney
Disease and help people lose weight some have been approved to treat obesity nausea diarrhea or vomiting are possible side effects of glp-1 medicines that often improve after a few weeks of use to manage nausea eat small meals that are light and low in fat and eat slowly to allow time for feeling full injectable glp-1 medicines can also cause redness swelling or
Pain at the injection site if symptoms are severe including stomach pain back pain severe nausea and vomiting please seek medical care glp-1 medicines carry a warning for a possible risk of certain thyroid cancers and a safety concern for use in people with pancreatitis tell your health care provider if you get a lump or swelling in your neck hoarseness trouble
Swallowing or shortness of breath see the medication package insert for a complete list of side effects and follow all manufacturer instructions glp-1 medicines may be able to help you reach your treatment goals talk to your health care provider about whether glp-1 medicines would fit into your treatment plan
Transcribed from video
Understanding the Role of GLP-1 Medicines in Managing Type 2 Diabetes By Med-IQ
