Hi so the drug that i chose for my research drug paper i chose try jardine as a diabetic medication it came out on the market on 227 of this year and the approval was joint through eli really and a company out of germany called the ranger engelmann it’s bohringer engelmann is one of the world’s top 20 pharmaceutical companies and its headquarters is in germany
Hodge rd is a combination drug and has three medications in it guardians trade jinta and metformin guardians is in a class of drugs known as the sodium glucose transporter 2 which is the sgl 2 t 2 inhibitors it works by prompting the kidneys to get rid of more glucose in the urine for jente belongs to a class of medications known as the dye peptidyl peptidase-4
Dpp-4 inhibitors it increases the amount of hormones that the that lower the blood sugar when it gets too high metformin the other the third drug in the and treasurer rd is in the class of medications called big big new knives the drug works by decreasing the amount of sugar cubes or from your food and the amount of sugar your liver makes it also increases your
Body’s response to insulin type 2 diabetes is a complex drug that often requires the use of multiple anti-diabetic medications to improve glycemic control having all three of these different diabetic medications and one tablet is an important advance in diabetes treatment my dad is a diabetic so i thought it was kind of interesting to try to learn more about the
Medications that are out there and available to those that have type-2 diabetes they are all separately well established therapies or type 2 diabetes it comes in four different dosages it is once a day you would take it with your breakfast in the morning you would take it along with diet and exercise and for those who adults who have already on treatment for type
2 diabetes but require extra agents to to get that healthy a1c and it hit that target the dosages are 5 milligrams 2.5 and a thousand that’s for one tablet the second dose that it comes in is 10 milligrams 5 milligrams and a thousand the third dose that it comes in is 12.5 2.5 and a thousand and the fourth dose that that trez already comes into our comes in two
Twenty-five five milligrams and a thousand milligrams you should never brush break cut dissolve or chew this medication i mean you just swallow it whole and if you can’t swallow the tablets then you would need to contact your doctor and see if there’s other options that are available he the triple combination treatment was based on findings from two randomized open
Label trials that assess the bioequivalence of true gentleness and metformin as well as their individual components together so it is not recommended for type one diabetes and not for anybody under the age of eighteen side effects are lactic acidosis pancreatitis and heart failure you can also get upper respiratory infection gastritis those are among the most
Common some serious effects are dehydration ketoacidosis kidney problems urinary tract vaginal yeast infections and hyperglycemia the combination drug is not recommended is contraindicated for people with kidney problems in stage renal failure or who are on dialysis those who also have metabolic acidosis you know a diabetic ketoacidosis or who are allergic to
Any of those three combinations of medications before starting this medication you need to discuss also with your doctor if you have any liver problems heart problems including chf if you’re over the age of 65 if you have history of urinary tract infections or problems with urination sorry my dog is wandering around out here if you’re planning on having surgery
If you’re eating less or there’s a change in your diet if you drink alcohol very often or if you binge drink if you have low levels of b12 or pregnant or planning on getting pregnant breastfeeding it can pass through the breast milk and could harm the baby also women who have not gone through menopause or does not have their periods regular at all actions of the
Medication jardin guardians is the proximal renal tubes and is responsible for the reabsorption of filtered and reduce the renal threshold of glucose therefore increasing urinary glucose excretion the another action of it is increasing in prolongs in chrétien integration of hormone activity those regulate homeostasis by raising insulin synthesis and release from
Pancreatic beta-cells and decreasing glucagon secretion from pancreatic alpha cells and then the metformin is the combination one of the medications in the combination it enhances glucose tolerance and vaso and post parental plasma glucose sorry guys i am nervous also guardians is one of the combinations that are in tragedy and it is used also for those that are
At risk for cardiovascular problems so that was kind of cold to me to that it was also one of the medications in there is also to help cardiovascular of course you would always need to followup with your doctor every three months and have your lab strong to check your numbers your levels and see how you’re doing follow diet and exercise also and there are lots
Of medications out there that interact with chardy topiramate drugs that interfere with common renal tubular transport systems in the renal elimination of metformin diuretics insulin some insulin and quarter stewards thyroid products estrogen birth control dilantin nicotine acid calcium channel blockers revamping ice and i side those you should also not take they
Can interfere with with the medication so that’s all i have for you guys think
Transcribed from video
Trijardy XR By Trina Lewis
