Drugs affecting the male reproductive system includes androgens or the male steroid hormones anabolic steroids and drugs that improve mental dysfunction but our topic will focus on panel erectile dysfunction drugs specifically with the dala field hey i am sialis and i am at the dollar field hi i’m anserka and i’m also a tadala field together we are the
Tabela phil sisters you will learn about our drug name true classification pregnancy category mechanism of action pharmacokinetics indications contraindications adverse and side effects and also the nursing responsibility fund’s names are cialis and ad my chemical name is so in the joint classification it is classified into two the therapeutic class in the
Pharmacological class the therapeutic class it serves as an erectile dysfunction drug and it is also a vasodilator wherein it relates or opens the blood vessels its pharmacologic class is that it is a phosphodiesterase type 5 inhibitor wherein it blocks phosphodiesterase type 5 by blocking it it causes blood vessels to relax increasing the blood flow to certain
Areas of the body my pregnancy category is b animal reproduction studies of me have failed to demonstrate the risk to fitness and there are no adequate and well-controlled studies of me than pregnant women next is this mechanism of action wherein it is classified into two its therapeutic effects and its chemical effect so let’s start with the chemical effect
Chemical effect is that i prevent breakdown of cyclic renaissance monophosphate by phosphodiesterase thus increasing cgmp level my therapeutic effect is that i prolong smooth muscle relaxation and promotes blood flow into the corpus cavernosum i am rapidly absorbed and by medium effects occurs in two hours i am distributed into tissues and a 94 protein ban i
Am metabolized by the liver by cyp 3a4 isoenzymes and excreted primarily as metabolized pieces and urine 61 increases 36 percent in urine my half-life is 17 hours the rate and extent of my absorption is not influenced by the food now we are in the indications men are indicated to take 10 milligram orally as a single dose as needed before sexual activity range
Is to 5 to 20 milligram based on effectiveness and tolerance maximum is one dose per day or 2.5 milligram amount daily without regard to sexual activity may increase to 5 milligram daily based on patient response the dose for patients with renal impairment if creatine and clearance is 31 to 50 ml per minute starting dosage is 5 milligram once daily and maximum
Dosage is 10 milligram taken once every 48 hours if 30 ml per minute or less maximum dosage is 5 milligram once every 72 hours for patients with mild to moderate hepatic impairment health bug class a or b dosage shouldn’t exceed the 10 milligram daily you should also adjust those four patients taking code at cyp3a4 or cytochrome p453a4 inhibitors such as ethromycin
Itraconazole ketoconazole and retinovar but exceed 110mg every 72 hours i am net advice as a causal treatment to patients that are hypersensitive to me or any of my components and to those who are taking nitrates or alpha blockers except themselves in 0.5 milligrams once daily patients with severe hepatic impairment myocardial infarction within 90 days i am also
Not recommended to patients with greater heart failure within 6 months stroke within 6 months uncontrolled arrhythmias blood pressure lower than 90 over 50 mmhg or higher than 173 170 or over 100 mmhg patients that has unstable angina or angina that occurs during sexual intercourse and has a cardiac status that makes sexual activity inadvisable and a patient
That has herded hereditary degenerative retinal disorder oh we are in the adverts and side effects in the central nervous system its effects include headache dizziness flushing seizures and transcend global amnesia in the cardiovascular system it includes hypotension flushing and qd prolongation in the integumentary system it includes steven stronsen syndra
Exofoliative dermatitis and portico eye ear nose and throat its effect may be a decrease or loss of hearing nasal congestion tinnitus vision loss bird vision changes in color vision and non-art direct systemic optic neuropathy in the gastrointestinal its effect may include this pepsia in the musculoskeletal system it includes bacteria lymphane and myalgia in
The miscellaneous it includes diarrhea heritage creatism and uti or urinary tract infection now we are in the last part which is the nursing responsibilities in the assessment part sexual activity may increase parts of risk assassin’s patients carter crisp first before he starts the drug or before he starts taking knee before a patient starts drug assess for
Underlying causes of vertical dysfunction next is you assess the patient’s and family’s knowledge of drug therapy assessment for a circa is the hemodynamic parameters at baseline and periodically meant for pregnancy or breastfeeding use only if purely needed but it is only applicable to uncirca cialis is not indicated for women not used in breastfeeding fears used
With caution in older adults it may exacerbate cinco so monitor frequently or sinkhole in diagnosis sexual dysfunction related to patients underlying condition risk for injury related to potential for prolonged erections and preactism and deficient knowledge related to drug therapy adding an implementation drug may cost enchant increase in supine blood pressure
And it may increase risk of prolonged erections patient teaching first this you warn the patient that taking drug with nitrates or alpha blockers could cause a serious drop in blood pressure raising the risk of heart attack or stroke second salvation to seek immediate medical attention if he develops chest pain hearing or vision problems after taking the drug
Third urge patient to seek emergency medical care if his erection lasts longer than 4 hours 4. tell patients take drug about 60 minutes before anticipated sexual activity explain that drug has no effect without sexual stimulation fifth warn patient not to change those unless directed by prescribers notify your physician about all medicines vitamins herbs
Being taken especially britannia beer indian aviar cataconazole italy conazole erythromycin nitrates alpha blockers the tadalafil is contraindicated for use with alpha blockers except 0.4 milligram per day times pseudo fashion patient against drinking large amounts of alcohol while taking drugs lastly evaluation sexual activity improves with drug therapy second
Patients sustain no injury from prolonged erection or priapism third improvement in exercise ability in pulmonary hypertension fourth patients and families state understanding of drug therapy additional informations if you’re wondering what we look like this is how we look like are you also wondering where to buy us then we are available to be purchased
In pharmacies or via online wow so that would be all i hope you learned something about us thank you god you
Transcribed from video
TADALAFIL by Sano and Yunson By Batch Kunzite