This video will contains information on new group of oral antidiabetic medications SGLT2 Inhibitors used for treating type 2 diabetes.
Hi friends welcome to my channel for medicos if you or anybody in your family is a diabetic patient then information in this video will be helpful to you this video will contains information on new group of oral medications sglt2 inhibitors used for treating type 2 diabetes before starting if you learn something or if you find information provided in this video
As helpful please motivate us by subscribing liking and sharing this video so let’s start sodium-glucose cotransport or to sglt2 inhibitors which are also known as glyphis ins are a new group of oral medications used for treating type 2 diabetes the drugs work by helping the kidneys to lower blood glucose levels sglt2 inhibitors have been approved for use as
A treatment for diabetes since 2013 they are taken once a day with or without food drugs in this class are the following drugs belong to the sglt2 inhibitors which are available in different trade names one dopa glyphis n’ to canagliflozin and three in piglet flows in how do sglt2 inhibitors work the kidneys work by filtering glucose out of the blood and then
Reabsorbing glucose back into the blood the proteins that reabsorb glucose are called sodium glucose transport proteins sglt2 inhibitors block these proteins which means less glucose gets reabsorbed back into the blood and gets passed out of the body via the urine hence sglt2 inhibitors work by preventing the kidneys from reabsorbing glucose back into the blood this
Allows the kidneys to lower blood glucose levels and the excess glucose in the blood is removed from the body via urine who are sglt2 inhibitors suitable for sglt2 inhibitors may be suitable for people with type 2 diabetes that have high blood glucose levels despite being on a medication regimen such as metformin and insulin sglt2 inhibitors are not recommended
For prescribing to people with kidney disease as kidney disease prevents the drug from working sufficiently well what are the benefits of sglt2 inhibitors sglt2 inhibitors help to remove glucose from the blood and therefore help to lower blood glucose levels and thereby decreases risk of complications of diabetes by removing glucose from the body sglt2 inhibitors
Can also have benefits for weight loss side effects of sglt2 inhibitors as the drugs cause more glucose to be excreted in the urine there is a higher chance of getting genital and urinary tract infections these side effects are more common in women than in men taking sglt2 inhibitors with insulin sulfonyl aureus or glein adiz may increase the risk of hypoglycemia
Sglt2 inhibitors can in rare cases lead to a dangerous condition called diabetic ketoacidosis thank you for watching this video please subscribe you
Transcribed from video
SGLT2 inhibitors (dapagliflozin, canagliflozin, empagliflozin) for diabetes: mechanism, side effects By D̷O̷S̷E̷S̷ O̷F̷ V̷I̷D̷E̷O̷S̷