1. What are the ADVERSE Effect of PHENYTOIN ? 2. What are the complications of PHENYTOIN drugs ??Headache, nausea, vomiting, constipation, dizziness, feeling of spinning, drowsiness, trouble sleeping, or nervousness may occur. If any of these effects persist or worsen, tell your doctor or pharmacistpromptly.
Hello viewers welcome to another session of my fabric odyssey series today i’ll be discussing about the adverse effect of one of the very common antiepileptic drugs that does phenytoin so the short track or the mnemonic what i have made to easily remember the adverse effects of phenytoin can be better remembered if we just look at the initials that does phen375 very
Easily relate the adverse effects with every alphabet of it so beginning with p so the first adverse effects of the phenytoin is that in the first per side effect the first adverse effect that is the p corresponds to the plasma level monitoring doctors on phenytoin administration plasma level monitoring is essential because of its zero order kinetics next the etch
Corresponds to the hypertrophy of the gums that does the gum hypertrophy can be seen so which can be minimized by having a maintaining a good oral hygiene the e corresponds to the enzyme induction so the use of phenytoin can lead to interaction with other anti epileptic drugs including other at epileptic antiepileptic drugs it can lead to interaction with other
Epileptic drugs so it is an enzyme an inducer or enzyme induction the end of the phenytoin corresponds to the neutropenia and other hypersensitivity reactions which can be illustrated if a chronic use of phenytoin is there so the why of the phenytoin corresponds to the young girls so in jungle should be bare when using phenytoin because it can lead to hirsutism
And cozening of facial features and acne so the young girl should be the why corresponds to the young girls they should beware when using phenytoin because it can lead to corseting of facial features hair so tourism and akane the t of the phenytoin that corresponds to the teratogenic effect so the married girl should beware should be aware because it can cause
Us it can cause fetal hydrant ines and rome so the t corresponds to the 30 of the phenytoin corresponds to duck teratogenic side-effects so married girls should beware because it can lead to fetal higher than joint syndrome the o of the phenytoin will correspond to the osteomalacia due to interference with the calcium metabolism so calcium absorption is impaired
So osteomalacia can occur the eye corresponds to the interference with the folate absorption so when the politte absorption is interfered it can further manifest in the form of megaloblastic anemia the last n of the phenytoin will correspond to certain side effects certain adverse effects can be seen by the n corresponds to certain neurological manifestations the
N stands for the neurological manifestations at higher doses on administering higher doses certain neurological manifestations can be seen in the form of a taxi a’ vertigo and nystagmus so viewers this was my analysis or the short trick as to how we can easily remember the adverse effects of phenytoin in the examination centre so viewers if you do like my video
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Transcribed from video
PHENYTOIN ADVERSE EFFECTS : Anti epileptic PHARMACOLOGY By Dr Anshuman Tripathi