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This video is about penicillins penicillins are one of the main drugs that inhibit bacterial cell wall synthesis so they are bacterial cellular synthesis inhibitors the other main drug that enables bacterial cell wall synthesis are cephalosporins in this video we’ll discuss about the structure and formation and attitudes of penicillins so first of all the
Structure of penicillins penicillins consists of a group which is known as its minor penicillinic acid and they consist of a beta let tamarind so what is a beta lactamarine a beta later brain is an unusual four-member vein structure and the beta latam is a basically a group of drugs that are cell wall inhibitors and they consist of a beta-lactam brain now the
Formation attitudes of penicillins first of all we will discuss about the form of administration of penicillins penicillins can be given orally but the resistance to gastric acid in their oral administration is variable and also their bioavailability in oral administration is variable the penicillins can also be given really which means in the form of injection
And they trans and the penicillins that are given in the form of parenteral administration are ampicillin represent antiquating now the metabolism of penicillins penicillins are not really metabolized because they are polar systems and they are not usually metabolized but there are exceptions to this the ampicillin and the naphthalene are metabolized they are
Metabolized in the liver and they are excreted in the bile now there’s tradition of penicillins like most of the drugs penicillins are restorated through the renal root that is through the kidneys and with kidney elimination there are two main processes by which the penicillins are eliminated which consists of blue material filtration and tubular situation the
Tubular situation of penicillin is inhibited by the drug protein acid and the probinis it is a drug that is used in doubt and hyperuricemia now the half-life of penicillins the half-life of penicillins is 30 minutes to 1 hour ueali but some forms of penicillin g some forms of penicillin g are given intramuscularly and they have a increased half-life because
When they are given intramuscularly they are transported to the bloodstream slowly and then the penetration of penicillins penicillins do not cross the blood-brain barrier so they cannot enter into the brains but when the meninges are inflamed for example in meningitis penicillins can cross the blood vein barrier so in meningitis spanish instinct throws a
Bedroom battery but you only do not cause a blood brain barrier in abstinence metabolizing the liver and restoration is to the renal root and the tubular situation is inhibited by provine acid half-life is 30 minutes to 1 hour except for any syringey and penetration cannot was a blunt wind barrier thank you
Transcribed from video
Penicillin pharmacology part 1-structure and pharmacokinetics -Beta lactam antibiotics -chemotherapy By Medical Study Life (Ordinary Medicose )
