Parkinson’s Disease is a neurological disorder. Dopamine allows the coordination of body muscles and movement. Patients with Parkinson’s Disease lose this muscle coordination. Signs and symptoms of Parkinson’s Disease include bradykinesia, postural instability, muscle rigidity and tremor.
Parkinson’s disease is a neurological disorder. the neurons in the sabstantia nigra in the brain die causing a deficiency in dopamine. bradykinesia (which is the slowness of movement), you can memorise these symptoms by pb as in postural instability and bradykinesia. symptom progression can causes severe disability,
And eventually progresses to the other side, now we are going to start with but before we do that make sure to hit that subscribe button. parkinson’s disease is levodopa, a precursor of dopamine. levodopa is given with carbidopa to prevent the metabolism of levodopa in the 25/100 mg tab taken 3 times a day. carbidopa
Must be taken at a dose of 70 to note that carbidopa/ levodopa must be separated from protein rich food. as the disease progresses carbidopa/ levodopa is not enough to help the patient so we catechol o methyltranseferase inhibitors, available with levodopa/ carbidopa under the brand name stalevo. adding entacapone
Allows us to decrease the dose of levodopa by up to 30%. this decreases the side another comt inhibitor is tolcapone. tolcapone another class of medication used to treat apomorphone is contraindicated in patients taking selegeline, rasageline and safinamide. note that safinamide causes severe hepatic impairment. and
Anticholinergics (such as benztropine & younger that 65 years old with resting tremor. the last medication we will be taking about, before we go amantadine is used as an antidyskinetic agent. and livedo reticularis. livedo reticularis is so how do we choose which medication to give? if the patient was started on levodopa/
Carbidopa if the patient is younger than 65 years if the patient is older than 65 years old, consider adding amantadine. dose, add amantadine if the patient wasn’t with this we reach the end of today’s video! don’t forget to comment down below what other until next time stay happy and healthy.
Transcribed from video
Parkinson's Disease Treatment Explained in 4 minutes By Key Concepts
