For the first time in over 50 years, we have a new type of estrogen in hormonal birth control pills!
In the last 50 years women have made some major strides we’ve seen the first female ceo the first woman to go to space and even the first female vice president of the united states but what we haven’t seen is any new types of estrogen and our combined oral contraceptives until now approved on april 16th of 2021 nextellus became the first birth control pill
To include estrogen this birth control is manufactured by main pharma it’s a company that produces several other birth controls including zovia microgestan and aaron something else to know this medication was developed by a company called mithra and they did it under the name estelle so you may hear both but either way this pill is different than other birth
Control pills that are currently available on the market nextellus is made up of three milligrams of gespirino and 14.2 milligrams of estrostrela also known as e4 you take one pink active tablet every single day at the same time of day for 24 days by mouth and then you’re gonna take one white sugar pill for every day for four days to complete the 28 day cycle
The part i’m about to get into can get a little confusing so if you have any questions drop them in the comments below i’m going to be doing a monthly q a session so i want to make sure i answer your questions and you have the chance to be featured in the video leave them down below 99 of oral birth control pills on the market include something called ethylene
Estradiol or ee for short this is a synthetic estrogen and there’s nothing inherently wrong with it it does a great job of preventing pregnancy which is the point of birth control pills for many women and this is similar to the body’s estradiol but the thing that researchers and scientists have been trying to figure out and work through to make this better is
That ethylene estradiol binds to estrogen receptors all over the body because estrogen is not just in your reproductive organs it is elsewhere as well and we don’t need that binding activity to occur to get the effect that we want in preventing pregnancy we just need it in certain parts of the body and that is where e4 comes in e4 is a human fetal steroid that
Selectively binds to the tissues in the body they’re responsible for cycle control and contraceptive activity it being selective in theory means there would be less side effects from binding in areas that are not necessary and while e4 is a human fetal steroid that’s not where they’re getting it from they’re actually deriving e4 from plants but it is chemically
Identical to what we see in the body naturally the other hormone that is used in this birth control is drosperanone and this is something that we see frequently in other birth controls it’s very common and together these two drugs work to stop ovulation which is required for pregnancy and in the clinical trials it did just that in the one year study that was done
There were 26 pregnancies in the 1524 females that were studied between the ages of 16 and 35 so roughly two in a hundred pregnancies which is on par with other birth control pills overall there were eight different side effects that occurred at a rate of greater than two percent during the clinical trials and over 50 of the women who were on this birth control
Method experienced some sort of adverse reaction during that year period the most common adverse effects were irregular bleeding problems this included not having a period at all mood changes headache breast tenderness pain or discomfort painful periods acne weight gain and decreased sex drive i think it’s also important to note that 9.6 of the women that were in
This clinical trial stop taking the medication in that year period due to some sort of adverse effect the most common reasons this was discontinued were bleeding irregularities new onset migraine and depression symptoms so overall you still will get side effects with this medication they didn’t go away but where it may be helpful is for women who have experienced
Pretty bad side effects or severe side effects with some sort of other birth control that has ethylene estradiol that they may not have that same reaction or as a severe reaction with this type of birth control next ellis is planned to be available sometime in june of 2021 and if you learned something in this video please give it a thumbs up it really helps this
Channel and make sure that you hit that subscribe button for more women’s health videos but for now check out the birth control playlists up on your screen right now thank you for watching and i’ll see you next time bye and then other birth control pills that are on the market 14.2 milligrams of estrogen estrostrela that was confusing similar to what we see with
Other birth control fills
Transcribed from video
NEXTSELLIS BIRTH CONTROL PILLS | Natural Estrogen (Estetrol or E4) Birth Control | Pharmacist Review By Happy Pharm Life
