In this episode, I discuss a medication known as nefazodone (Serzone).
Everybody welcome back to drug talk is always am your host garrett campbell erica me discussion of medication known as methadone its brand name is serisone and before i talk about the medication itself just keep in mind that this channel is for information purposes only and not to be used as a source for recommendations for your personal healthcare anif acetone
Is an antidepressant agent derives from phenyl piperidine its exact mechanism of action is still currently unknown however it’s thought that its action is caused by its ability to stop the reuptake of norepinephrine and serotonin in terms of indications for use the fazer donas indicated to be used in the treatment of mdd or major depressive disorder before
Somebody was to use mm own there are some contraindications that they must clear as well as some precautions and warnings that they should be made aware of this medication cannot be used by patients who are using triazole ‘m if a patient has a hypersensitivity tunip acid own any other component of the product as well as other phenyl piperidine antidepressants
They would not be able to use this medication and if somebody had to stop using the facet own in the past due to liver injury they would also not be able to use this medication now in terms of precautions patients should be made aware that sinus bradycardia or a slow heart rate as well as orthostatic hypotension which is a sudden drop in blood pressure when going
From a seated to a standing position have both been reported patients should be told to avoid using alcohol with methadone it’s not recommended to use this medication within 14 days of a mono aiming oxidase inhibitor patient should be made aware that convulsions including grand mal seizures have been reported with the use of methadone and visual disturbances
Including blurred vision have also been reported patients must be screened for bipolar disorder before staring this medication as it may precipitate manic or mixed episodes and lastly for precautions male patients should be made aware that priapism has occurred and if this was to occur the medication should be discontinued now once somebody is cleared up the
Contraindications and made aware of the precautions and warnings and they start to use in the fazer dome they can expect to receive their dose orally so if somebody is using the thousand own to treat mdd or major depressive disorder they would we start off with 100 milligrams taken twice daily dose can then be increased by 100 or 200 milligrams daily each week
To a maximum dose of 600 milligrams per day as with all medications there are some side effects or adverse reactions the patients may experience while using the faz adone so i’ll go over some of those here now we mentioned orthostatic hypotension was a possibility this can happen up to 4% of the time up to 17% of patients may experience constipation and up to 23%
May experience nausea dry mouth comes in at a rate of 25% and up to 7% of patients may experience confusion dizziness can happen up to 22% of the time and the headache may occur up to 52% of the time the percent of patients may experience lightheadedness and up to 32% may experience somnolence third vision can happen between 3 and 9 percent of the time some more
Rare but serious side effects will be a dermatological reaction known as steven johnson syndrome liver failure they are tonin syndrome priapism or angioedema the dogger talked about today with methadone or serisone as always i’m very thankful you took the time to come by and watch one of my videos if you found the information valuable you’d like to help grow
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Transcribed from video
NEFAZODONE (SERZONE) – PHARMACIST REVIEW – #200 By Drug Talk