Clinical Cousins cover Phenytoin (Dilantin) in their effective and concise “Minute to Master” series.
Hello everyone and welcome back to clinical causes youtube channel where today we’re going to go over the drug pheneline also known as delanten this drug is classified as an anti-convulsant in class 1b anti-dysrhythmic medication it is mainly given to prevent and treat seizures now when this drug is given for a seizure cardiac arrhythmias and severe hypotension
May occur so use careful cardiac monitoring also do not administer this drug with other cns depressants in pregnant women this drug may cause fetal harm now what we need to know is that this drug will bind to and stabilize our neuron membrane as we already know seizures are simply electrical storms in the brain in other words seizures are the result of overactive
Or over firing neurons normally it is very important that we know that the neuron is lined with voltage-gated sodium channels when the neuron reaches threshold these channels open and an action potential message is sent from one neuron to another neuron the lantern is believed to block sodium from entering the neuron this means that our neuron will never make
It to threshold and its activity will be decreased this is how deland prevents seizure activity it simply decreases the amount of ions or electrical activity in every single neuron now you should also be aware that patients with low blood albumin are more likely to experience deland toxicity why is this the case because if your patient has low albumin levels
And we have a highly protein bound drug like the lantern if there are not enough protein binding sites there will be more free the lantern that is allowed to circulate this increases the chance that your patient will experience the lantern toxicity some of the signs of deland toxicity are mostly neurologic are things like ataxia nystagmus or even coma also
Long-term use of this drug can cause gingival hyperplasia or gum overgrowth this joke’s onset and duration are determined by the root id administration has a rapid onset while po administration has a slower onset in a longer duration the side effects of this drug may include drowsiness ataxia gingival hyperplasia gi upset and even cns depression some commonly
Tested material about this drug is that this drug is given to prevent and treat seizures it can cause gingival hyperplasia with long-term use and you should monitor your patient for neural and cardiac adverse effects as always thank you so much for taking the time to learn with us today and remember to like and subscribe for more content
Transcribed from video
NCLEX Prep (Pharmacology): Phenytoin (Dilantin) By Clinical Cousins
