🩹 Dermatology Course:
Welcome back in this video i’ll be teaching a mnemonic that i came up for amyloid arthritis which includes all the features and characteristics of this disease first let’s talk about the pathogenesis of rheumatoid arthritis it’s an autoimmune disease relating to hla d4 and this will cause granulation and destruction it’s a systemic disease so symptoms will appear all
Over the body and there are two main antibodies in rheumatoid arthritis the robotoid factor which is called an t immunoglobin antibody it’s basically antibody against antibodies and it’s present in about 80% of the cases and there is an t cycle accent related peptide antibodies which is the most specific factor for rheumatoid arthritis remember all the symptoms and
Characteristics of rheumatoid arthritis i remember the word inflamed so i for inflammation of the pleura and the pericardium and for nodules are there in the skin or in the lungs and the skin will call them rheumatoid nodules they’re just fibers nodules and in the lungs will call them pneumoconiosis or kaplan syndrome f450 syndrome which is basically splenomegaly
That is induced by rheumatoid arthritis ll for lack of saliva which is caused by sjogren’s syndrome and associated with rheumatoid arthritis a for anemia of chronic disease m for median nerve compression which is caused by carpal tunnel syndrome efore i sclerosis in bonn changes will see subchondral origins as you can see and sub country assists and here are
The subchondral origins and sits next to one another so you can compare them as you can see the erosion is more diffused and the cysts are more circular in shape there is also subconscious chlorosis the decrease in the joint space and finally on a subluxation of the fingers to treat humanoid arthritis who use the disease modifying agents such as methotrexate
Sulfasalazine hydroxy chlorine and left an amide and we use biological agents like tumour necrosis factor-alpha inhibitors which will inhibit the granuloma formation and first symptoms relief will give nsaids and steroids all right guys that’s everything about your much other authorities that you need to know for step one these are all the features that you will
See other grossly on the lab or i can serum whatever so hopefully i made this easier for you and until you guys later
Transcribed from video
Methotrexate, Hydroxychloroquine, Sulfasalazine, Mycophenolate, Leflunomide, and Cyclophosphamide By USMLE pass