What is PEP? PEP (Post-Exposure Prophylaxis) is antiretroviral therapy where individuals take medications orally in order to reduce the chances of acquiring HIV following possible exposure, which may occur from contact with bodily fluids either through sexual activity or injections. This video provides an overview of how PEP works to reduce the chances of acquiring HIV and discusses the effectiveness of the drug zidovudine as part of a case-control study. Zidovudine is a type of antiretroviral medication that is a controlled drug that must be proscribed by qualified medical professionals.
Welcome back to the mystifying medicine series today we’ll be talking about post exposure prophylaxis which is a possible trainer for hiv if taken immediately after exposure if you want to learn more about hiv please visit the demystifying medicine page or click the video link below let’s give a pep talk meet joe joe is a young adult and like most young adults
Joe likes to party occasionally joe meets a special friend when he goes el and if he’s really lucky to decide to come home with them like tonight let’s not get into too much detail what happens next you get the idea the next morning joe wakes up and goes about his normal routine later that day joe attends a dhimmis of my medicine class where he watches the video
Book hiv joe panik when he remembers he did not use a condom last night and i sex with a complete stranger ball in class joe runs to the nearest sexual health clinic where he explains his worries to the doctor the doctor tells him about post-exposure prophylaxis also call me known as path the doctor’s planes that path is a form of antiretroviral therapy pap is
Taken orally and the current most common prescribed form pep consists of one dose of truvada and two doses of the centrist which are taken daily truvada is a reverse transcriptase inhibitor meaning inhibiting inversion of the viral rna to viral dna where the centrist is an integration hibbett er which prevents a viral dna from being integrated into the genomic dna
Of the cell both these mechanisms are important in the reproduction of the hiv virus within the immune cell but with the help of pap the production of the hiv virus is suppressed the doctor warns joe that according to a case control study not on health care workers exposed to hiv positive blood through either a needle or sharp object found that a similar reverse
Transcriptase inhibitor 0vu 9 is only about 81% of but to reach this level of effectiveness it must be taken for all 28 days and treatment must be started within 72 hours of exposure he is also called he needs to come back after six weeks and four months from mandatory hiv antibody testing after he prescribed a peb joe first relieved and decisive stick to the 28-day
Routine while on ped joe realized that it’s not always sunshine and daisies since during the medication he’s experienced side effects such as abdominal pains headaches rashes diarrhea and husband fatigue although joel’s result ended up being negative half for the four-month mandatory hiv antibody testing it is still recommended that pap is only taken in emergency
Situations practicing safe sex with the use of condoms and using per minute of exposure for faxes are more effective at ensuring that hiv is not transmitted at the end of the day be like joe contact a health care professional when in doubt an discover what options are available for you a message brought to you by mcmasters demystifying medicine page you you
Transcribed from video
Let's Give a PEP Talk! An Antiretroviral Therapy for HIV Prevention By Demystifying Medicine McMaster
