Empagliflozin for Type II Diabetes.
Hi my name is tuivo and i’m going to be talking about empigliflozin brand names guardians so a bit of introduction on giardians it is a sglt2 inhibitor there are desirable side effects for type 2 diabetes patients such as weight loss and reduction in major cardiovascular events and mortality it is indicated for type 2 diabetes patients as an adjunct to die
In exercise to improve glycemic control and also a risk and reduction of cardiovascular mortality in patients with type 2 diabetes and also decreases a1c by 0.7 to 1 percent so patient counseling on giardians includes you want to take this medication in the morning yeast infections of the penis or vagina can occur while taking this medication tell your doctor
If you develop any odor discharge itchiness or pain in the genital area this medication can cause increased urination and dehydration which is a loss of too much body water resulting in dizziness lightheadedness weakness fainting and thirst this can lead to sudden injury of the kidneys tell your doctor right away if you are sick and cannot eat or drink or if
You lose liquids due to vomiting diarrhea or being in the sun for too long this medication can cause a serious condition called ketoacidosis which can lead to death tell your doctor right away if you develop nausea vomiting tiredness trouble breathing or stomach pain infections of the urinary tract can occur while taking this medication tell your doctor if you
Have burning or pain when you urinate i need to urinate frequently and urgently having pain in lower part of your stomach or blood in the urine especially if you have a fever some mechanism of action of guardians is that it is expressed in proximal renal tubules it is responsible for reabsorption of filtered glucose from tubular lumen and inhibits sglt2 these
Drugs reduce reabsorption of filtered glucose and lower renal threshold for glucose and this increases urinary glucose excretion and decreases plasma glucose concentrations so dosing and adjustments for guardians it starts off at 10 milligram daily in the morning this can be increased to 25 milligram daily and if patient has a egfr less than 45 then this is
Not recommended for the patient so warnings and side effects for giardians include a black box warning for risk of leg and foot amputations we need to evaluate the risk prior to treating the patient by looking at history of amputation peripheral artery disease peripheral neuropathy and or diabetic foot ulcers other side effects include weight loss hypoglycemia
Increase of urination increase thirst and increase magnesium phosphate and potassium monitoring parameters for guardians include renal function blood glucose a1c ldl blood pressure and volume status
Transcribed from video
Jardiance for the treatment of Type II Diabetes By Riverside Rx Services
