In this video you are going to see about the inhaled corticosteroid, which is mainly used to treat the symptoms of allergic rhinitis.
Greetings to the viewers of this video in this video we will have a look upon the drug futicus and furoat a corticosteroid medication primarily used to treat allergic rhinitis it delivers 27.5 microgram per spray it delivers totally 120 meter dose the composition of this spray are as follows futicus and furoat 0.055 percent weight by weight benzoliconium
Chloride added as preservative 0.015 percent weight by weight excipient quantity sufficient futicus and furoad is a synthetic trifluorinated corticosteroid that possesses a very high affinity for the glucocorticoid receptor and has potent anti-inflammatory action so it is used to treat symptoms of allergy next is dosage and administration the recommended
Dosage for adults and adolescents that is 12 years and above is two sprays in each nostril once daily total daily dose is 110 microgram for children between the age of 2 to 11 years the recommended starting dose is one spray in each nostril once daily the total daily dose is 55 micrograms no dosage adjustment is needed for elderly hepatic and renal impaired
Patients futicus fluticasin furoad is for intranasal use only now let us see special warnings and precautions the first one is drug interactions futicusan fuerot is a corticosteroid metabolized in liver by siva ap3a4 enzyme so inhibitors of cyp3a4 enzyme such as ritonavir ketoconazole verapamil erythromycin should not be co-administered with futicus and
Furoad because of potential risk of increased systemic exposure it is particular for high doses next is growth retardation a reduction in growth velocity has been observed in children treated with futicus and furore 110 microgram daily for one year so children should be maintained at the lowest dose possible next is ocular changes potential systemic steroid
Effect on eye is central serous chorioretinopathy it is safer to use in pregnancy and lactation if used at the recommended therapeutic dose adverse drug reactions are as follows first is respiratory thoracic and mediastinal disorders in this case nasal ulceration and epistaxis are very common some of the uncommon effects are nasal dryness rhinalgia and
Nasal septum perforation next is musculoskeletal and connective tissue disorder growth retardation in children immune system disorders such as anaphylaxis angioedema rash also occur headache is very common next is pharmacokinetics absorption futicus and furoat undergoes incomplete absorption and extensive first pass metabolism in liver and gut resulting
In negligible systemic exposure distribution the plasma protein binding of fluticason furoat is greater than 99 percent metabolism futicus and fuerot is rapidly cleared principally by hepatic metabolism to an inactive 17 beta carboxylic metabolite next is elimination elimination of this drug is primarily via the fecal route it is also excreted in urine if you
Want to know how to use a nasal spray check out the video in the description box below thanks for watching have a great day
Transcribed from video
Inhaled Corticosteroid – Fluticasone furoate – Allergic rhinitis By World Of EduPharmaliveBroadcastDetails{isLiveNowfalsestartTimestamp2021-10-10T134225+0000endTimestamp2021-10-10T135001+0000}
