Hello my name is yana kawaha my topic is inhale be designated from the prevention of bronchopulmonary dysplasia definition directly clay administration of health corticosteroids may allow for beneficial effect on the pulmonary system of infants which involve or establish glanco pulmonary dysplasia bpd with a lower risk of underlying seal effect compared to
Semi-corticosteroids among other things i’m going to present the results of the so-called neurosis study neurosis is an acronym it stands for the neonatal european study of inhaled spirits and this study was mainly funded by the european union in its seventh framework program but it was also partially funded by a pharmaceutical company that was not otherwise
Involved in any aspects of the study so you may have recognized that the title of my presentation is early corticosteroids for the prevention of epd so the first question i ask myself and i want to answer in this presentation um so to be more precise what do the three letters be d actually stand for so i did what everybody does these days i went to the internet
And i typed into google the three letters and here’s what i found so there are lots of different definitions for the three letters bpd so as you can see it starts with borderline personality disorder it continues with bipolar disorder there are also some interesting things for example here is the beach party division but you already know i’m not going to talk
About the beach party i’ll talk about corticosteroids and for the prevention of bronchopulmonary dysplasia so now at least you know what the three letters stand for but you don’t know what bronchopulmonary dysplasia is and that’s a much more complicated question to answer we could discuss for hours days weeks some international comedies right at the moment even
Take years application in nursing systemic glucoreticoids have been reduced the incident from bronco dysplasia but they may cause short long-term embarrassed effect including perforation and serial pcb is increasing gene repression which results in production the formation of cytokinesis factor it also stops the activations increasing and finally suppressing
The activation of inflammatory cells from mast cells macrophages the application in nursing systemic glucosicoid reduce the incidence of bronco pulmonary displesia among escalators fans but they may come from his brain development inflammation has always been associated with bpd i really believe it’s because of the inflammatory process that occurs when you
Feed a baby cow’s milk products it’s a foreign protein it used to be our only choice we have to fortify these babies and all we had was cow’s milk now we have human milk human milk for human babies molecular bioscience makes fortifiers out of human milk and human milk allows us to feed babies early and quickly and not cause the inflammatory response that foreign
Proteins like cow milk products cost and so if we can give them human milk we can fortify early we can feed early and we are seeing decreases in bpd bpd is decreased in study after study we’re seeing abstracts at conferences now where repeatedly bpd has been decreased in infants who are fed exclusive human milk to not have bpd is a huge thing isu applied to
Ecuador we friendly and site sign 863 infant chechen like eg 23 week all day to 27 which 6a too early will 24 heart afraid will have destiny they are civil i lose they no longer rukai oxygen um positive pressure supper or night they ratio a person’s throat eg of thirty through a weight or date the primary outcome waste like or bronco pulmonary displacement
Confirming the remains of the stairs tanis oxyhistorization monitor at hypermistral issue of 36 queen is also known as chronic lung disease of prematurity or cld it is defined as a prolonged oxygen unit you usually need that oxygen at 36 weeks gestational age bpd likely begins with altered lung development before birth it is associated with infants who are
Small for gestational age who may have a genetic susceptibility to developing abnormal lungs and in babies whose mothers smoke apd can be started with the need for a lot of resuscitation at birth babies who are depressed at birth who are severely ill and who need a lot of intervention just to make it to the nicu are at highest risk for bpd there are other risk
Risk factors that are associated with development of bpd after birth the biggest one is degree of prematurity the younger the baby the higher the risk for development of bpd prolonged mechanical ventilation or a long time on the ventilator puts the baby at high risk and that is why we’d like to extubate babies as soon as possible to see that reintubation for
Any reason increases the baby’s risk for bpd some reasons that babies are often re-intubated and put back on the ventilator in the nicu conclusion among extremely pro-infants the incident of problem pulmonary dysplasia was what lover mom does how resilient early he had pedestal neither that among those who read it placebo in the old bronco bronchopulmonary
Species we were talking about babies beat retail represent at around the circular stage or even after this angular stage when most of the lung tissue has been formed and then we introduce the mechanical ventilation to these babies the effect here is disturbance to the normal growth and the result will be airway injury inflammation and parenchymal fibrosis due to
Mechanical ventilation and oxygen toxicity as you can see from the histopathology picture here if we compare it to the new bpd we are talking about the risk of development of the amount of development so usually at the canonicular stage and the problem here is
Transcribed from video
Inhaled Budesonide for the prevention of Bronchopulmonary Dysplasia By Elizabeth Cauja