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Immunosuppressants/DMARDs – Pharmacology (Pharm) – Immune System -@Level Up RN

Posted on November 4, 2022 By
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Immunosuppressants, which are also DMARDs (disease modifying antirheumatic drugs). Important nursing care and patient teaching for patients taking immunosuppressive medications. The following specific immunosuppressive (DMARD) agents: methotrexate, cyclosporine, and hydroxychloroquine.

Hi, i am cathy, with level up rn. in this video,  i’m going to begin my coverage of immune system   medications. if you have our pharmacology second  edition flashcards, definitely pull those out   so you can follow along with me. specifically in  this video, i will be covering immunosuppressants,   to test your knowledge of

Some of the key  facts that i’ll be covering in this video.   get into specific medications, i want to talk   to you a little bit about immunosuppressants in  general, because any time we suppress a patient’s   immune system, it makes them more likely to get  an infection because their immune system is not   able to

Fight off those pathogens as well.   so in terms of nursing care of a patient who’s on  an immunosuppressant, we want to closely monitor   their temperature, their white blood cell count.  we want to limit visitors. we also want to limit   fresh flowers or plants in the patient’s room. and  then we want to provide teaching to

The patient as   well to help them prevent getting an infection.  so they should have really good hand hygiene.   they should avoid sick people and crowds. they  should make sure they get their vaccinations,   make sure they cook their foods thoroughly. so  this teaching and those nursing interventions   all right,

Let’s get into specific medications  starting with methotrexate, which is an   anti-metabolite. methotrexate is used to treat  autoimmune disorders such as psoriasis and   rheumatoid arthritis. it is also used to treat  certain types of cancer and to dissolve ectopic   pregnancies. so its mode of action is that it  causes

The death of rapidly replicating cells and   also has an immunosuppressive effect in the body.  due to that immunosuppressive effect, a key side   effect with methotrexate is going to be infection.  other side effects include hepatotoxicity,   bone marrow suppression, gi upset, stomatitis,  which is painful ulcerations in

The mouth.   methotrexate also has a black box warning due  to the risk for fetal death and fetal toxicity.   so pregnant women are definitely not going to be  taking methotrexate. we talked through some of the   with protecting the patient from infection.   other nursing care associated with methotrexate  includes

Monitoring the patient’s liver function   because of that side effect of hepatotoxicity,  and also monitoring the patient’s cbc levels   so the way we remember this medication and   what it’s for in our little cool chicken hint on  this card, if you look at methotrexate, you see   t-rex in the name. so i think about a t-rex

Who  has to move around very slowly because it has   rheumatoid arthritis, and so it needs methotrexate  in order to treat its rheumatoid arthritis.   mnemonic to help everyone remember what   in the comments so we can all benefit from it.  next, we have cyclosporine, which is a cyclic  polypeptide. it’s used to prevent

Organ rejection   in transplant patients. it’s also used to treat  autoimmune disorders such as ulcerative colitis,   rheumatoid arthritis, and psoriasis. it works  by inhibiting the body’s normal immune response.   so key side effects with cyclosporine include risk  of infection because it’s an immunosuppressive  

Agent. other side effects include hepatotoxicity  nephrotoxicity, gi upset, hypertension,   and tremor. this medication carries a black box  warning because it can cause the development of   we’re going to do all the teaching and care to   help prevent infection in the patient. we’re also  going to closely monitor their liver

Function and   their kidney function because of the side effects  of hepatotoxicity and nephrotoxicity. also, if   the patient is taking this because they received a  transplant, they need to know that they will need   to take cyclosporine for the rest of their lives.  so it’s not going to be a short-term-type therapy. 

Which became kind of famous during the covid-19  pandemic. hydroxychloroquine is used to treat   autoimmune disorders such as rheumatoid arthritis  and lupus. it is also used to treat malaria.   include gi upset, vision changes, seizures,   the number of granulocytes in the body, which   is a type of white blood cell. so in

Terms of  nursing care, we’re going to want to monitor the   patient’s cbc levels during therapy, and we also  want to advise the patient to take this medication   with food in order to help reduce the gi upset  that is common when taking hydroxychloroquine.  first question, what is the key side effect that  we need to know for

All immunosuppressive agents?   all the nursing care and patient teaching   patients taking immunosuppressive agents.   agent is used to dissolve an ectopic pregnancy?   question number three, what medication is used to  prevent organ rejection in transplant patients?   you did well with that quiz. if you got  

And read the flashcards, do some repetition   is where it’s at when it comes to pharmacology.   i invite you to subscribe to our channel and share   a link with your classmates and friends in nursing  school. if you found value in this video, be sure   and hit the like button, and leave a comment and  let us know what you

Found particularly helpful.

Transcribed from video
Immunosuppressants/DMARDs – Pharmacology (Pharm) – Immune System -@Level Up RN By Level Up RN

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