Estrogen is a hormone associated with female sex and is responsible for the development of female sexual characteristics.
Estrogen is a hormone associated with female sex and is responsible for the development of female sexual characteristics there are three major endogenous estrogens that have estrogenic hormonal activity estrone estradiol and estriol estradiol is the most potent and prevalent the effects of estrogens on the body breast estrogen is responsible for developing breast
And mammary gland tissue it causes breast development during puberty in females estrogen is also responsible for the development of mammary ducts during puberty and pregnancy functions to secrete breast milk in postpartum lactation estrogens thickening the endometrial lining in preparation for pregnancy vagina estrogen supports the proliferation of epithelial
Mucosa cells of the vagina and the vulva in the absence of estrogen the vaginal and vulva mucosal epithelium becomes thin and presents with symptoms of dryness known as vulva vaginal atrophy during puberty estrogen aids in the development of long bones and fusion of the epiphyseal growth plates estrogen protects bones by inactivating osteoclast activity preventing
Osteoporosis in both estrogen-deficient and post-menopausal women cardiovascular estrogen affects plasma lipids by increasing high-density lipoproteins hdl and triglyceride levels while decreasing low density lipoproteins ldl and total plasma cholesterol and reduce the risk of coronary artery disease in early use in post-menopausal women estrogen or estradiol is
The most common form of estrogen hormone for fda approved treatment as hormone replacement therapy clinically the use of estrogen includes the following fda approved indications primary ovarian insufficiency female hypogonadism symptoms associated with menopause including vulva vaginal atrophy dysporunia hot flashes and night sweats and prevention of osteoporosis
Oral contraceptive pill ocp to prevent pregnancy moderate acne vulgaris prostate cancer with advanced forms of metastasis estrogens are in male body also while estrogen levels are significantly lower in males than in females estrogens nevertheless have important physiological roles in males the balance of two steroid hormones androgen and estrogen plays an important
Role in male reproductive organs and is essential for normal prostate development and prostatic homeostasis however estrogen signaling also plays a role in maintaining the male reproductive system air is expressed in prostatic tissues during fetal development estrogens are steroidal hormone which means it reaches cell nucleus and induced dna transcription natural
Estrogen and synthetic estrogen may cause the following common adverse effects breast tenderness nausea vomiting bloating stomach cramps headaches weight gain hyperpigmentation of the skin hair loss vaginal itching abnormal uterine bleeding also known as breakthrough bleeding and anaphylaxis weight gain may be a reported adverse effect of the oral contraceptive pill
Ocp containing ethanol estradiol but studies conducted on short-term and long-term use of ocps resulted in no weight gain association more severe but rare side effects of estrogen include hypertension cerebrovascular accident myocardial infarction venous thromboembolism pulmonary embolism exacerbation of epilepsy irritability exacerbation of asthma galactoria and
Nipple discharge hypocalcemia gallbladder disease hepatic hemangioma and adenoma pancreatis breast hypertrophy endometrial hyperplasia vaginitis vulva vaginal candidiasis intravaginal preparations enlargement of uterine fibroids and risk of cervical cancer and breast cancer box warnings the use of estrogen without progestins increased the risk of endometrial cancer
The use of estrogen with and without progestins resulted in an increased risk of myocardial infarction stroke pulmonary emboli and deep vein thrombosis in postmenopausal women 50 to 79 years old and an increased risk of invasive breast cancer in post-menopausal women 50 to 79 years old with oral conjugated estrogens with metroxoprogesterone by studies established
By the women’s health initiative the use of all conjugated estrogens plus metroxoprogesterone acetate increased the risk of developing dementia in post-menopausal women older than 65 years of age have been established by the women’s health initiative memory study
Transcribed from video
Estrogens – Female sex hormones – what is estrogens function? By Kote’s Medical Animations
