Uh hello everyone my name is uh search clean and i’m a resident from weaver uh regional clinical hospital ukraine uh first of all i would like uh to thank for the opportunity to present uh our work and management of moderately severe achievement creatities uh i have no disclosure uh active pancreatitis is a big problem in modern world mortality in patients with
Severe acute pancreatitis reaches thirty percent but the genesis of acute pancreatitis is very difficult and for third reason there is no uh pathogenic treatment uh for this disease a standard treatment includes infusion turrets with painkillers and symptoms therapy uh it’s well known that acupuncturist is followed by a hypercalculation state uh that’s why
It makes sense to add an inductor gland to the treatment good candidate for that is an oxyporin that has numerous anti-inflammatory efa effects it blocks a pro-inflammatory hematine-mediated hemotaxis activation of t-cells hemoglobin-mediated regional transmigration so the aim of our study was to investigate an effect of an occupying patient with a moderately
Severe acute pancreatitis for that we took 98 positions and divided them for two groups the first group became standard treatment of a plus anoxifying one mega milligram per kilogram once a day for 12 days and a control group 63 patients uh with just a standard treatment as you can see the checkpoints were at the first day a third day seventh day and the fifth
Fourteenth of the day we measured uh some uh pro-inflammatory cytokines and crp and also done a hologram and the dimer uh so as you can see color ground normalization faster in the group with an occiparine and but the biggest question was in the group were like with a dimer uh in the group with an occipatory it’s a constantly decreased but in the group without
The anticoagulant it’s a just increased what about the level of uh proliferation pro-inflammatory cytokines and acrp there are levels also decreased much faster in the group with an octoprint uh levels of interleukin 6 and a crp on day 4 14th in the group with antico glen was twice lower than in the group without it for the evaluation of clinical status we
Used apache sex to score and in the group is an occipating uh it decreased much faster than a group without it in the group with an occiparin mortality was almost three percent uh but without it almost eight percent uh thirty percent of a patient without an occupant needed open necrox and just eleven percent of the patients in the inoxiparing group uh so in
Conclusion i would like to say uh say that an occipital improves outcomes in patient business this va cured pancreatitis and occipital implication reduce inflammation process and percolation state improved the condition of patients reduce our morbidity level of course our study was uh very small and now uh randomized uh but we hope that it encourages another
Researcher for future investigation in this field and do some big placebo control multi-center randomized trial so thank you for your intention and have a good time on this conference
Transcribed from video
Enoxaparin in the management of moderately severe acute pancreatitis patients By American Pancreatic Association
