Use this IB-MD to quickly learn about the drug cyclosporine in a way you will never forget! Check out our site at www.doctoredimagesmd.com for more, and the video explaining Th1 and IL-2 here:
Everyone i’m sebastian with doctored images md and today we’re going to talk about the cyclosporine with the unicycle riding sport now you can see here we’re deleting parts of an old image we created that you can go back and watch we’ll provide that link below all that we’re gonna leave over is the th one for the t cell and il-2 down here and that’s because we’re
Going to talk about the drug cyclosporine the unicycle riding spore and its main job is blocking t-cell activation by blocking il-2 transcription so let’s go ahead and get started the first thing we’re gonna see here is our cyclosporine he’s a spore riding on this unicycle now in order to help him ride the unicycle we have this little fellow cyclo filling it’s a
Unicycle with fill from modern family helping cyclosporine ride that unicycle and that’s because cyclosporine buying cycle of filling together these will regulate and suppress il-2 and il-1 production by regulating gene transcription we can see here they’re running over the baby form of il-2 and breaking its sword in half and squishing it and that represents the
Mrna that they are blocking yes now we can see this zigzag path we’ve added here that shows the path cyclosporine has written and on that path right in the middle on a broken unicycle crying on the ground is this big eared elephant esque fellow now this elephant as fellow is calcineurin and that’s because cyclo fill-in and cyclists board together are going to
Inhibit calcineurin calcineurin is the calcium surrounding this big eared fellow laying on the broken unicycle and we’ll see this again in a video following this one about tech rolling this now let’s talk about what is in cyclosporine hand and that’s this sippy cup the three a sippy cup and that stands for cyclo spora and being metabolized by sip 3a this means
There’s grapefruit and drug interactions dealing with anything that activates or blocks sip 3a activity now let’s move on to the side effects the primary side effect that you definitely want to know is gonna be the nephrotoxicity this represented here by reoccurring civil scene drug videos with nephrotoxicity and that’s the broken toilet with the loop of henle
Going over it we’ve also added potassium ions in the seat of broken toilet and this stands for another side effect that can occur and that’s hyperkalemia this also means you should be careful of the use of cyclosporine with the test impairing diuretics or just be aware that it could increase the chance of hyperkalemia occurring let’s move on to the hypertension
High-wire this is another reoccurring similar this it’s the fact that hypertension is the side effect that can occur on top of our hypertension high wire we’re and have another reoccurring symbol the hyperlipidemia adipose blob he’s carefully walking across the hypertension high wire now we’re gonna add a beard and some armpit hair to the hyperlipidemia it doesn’t
Seem like much of a problem except we’re also gonna add this hairstyle that tells you that our adipose blob is in fact a woman now she definitely doesn’t want this big beard and armpit hair this stands for other side effect hirsutism so overall we have our unicycle riding cyclosporine binding to philip binding to cyclo fill-in blocking il-2 production at the level
Of gene transcription thus suppressing t-cell activation this is used mainly for transplant rejection prophylaxis and rheumatoid arthritis and that’s all again i’m sebastian with doctored images md have a productive day
Transcribed from video
Cyclosporine By DoctoredImagesMD
