In gram-positive bacteria cephalosporin penetrates the peptidoglycan layer and binds to the trend peptidase or what is called the penicillin bond in protein or pbp blocking its activity which leads to a failure of cross-linking between the 2 glycoprotein polymers this stops the pedicle like and synthesis causing a damage to the peptidoglycan layer there for syphilis
Boring has bactericidal effects on gram positive bacteria some gram positive bacteria can release a beat up like the moniz enzyme outside the pedicle i can layer this enzyme binds to the beta-lactam ring of sets of cephalosporin and breaks this ring this consequently impairs the ability of cephalosporin to bind and block to the pvp and loses its effect clove onic
Acid can be added with the cephalosporin clove onic acid contains a beta laxman ring and has a high affinity for the binding to the beta lactamase ends on this blocks the activity of this enzyme therefore cephalosporin can bind and block the activity of pvp leading to a failure of cross-linking of the two like a protein polymers stopping peptidoglycan synthesis
Causing a damage to the epic lichen layer therefore cephalosporin with cloven ik acid has a bactericidal effect on gram positive bacteria that can release the enzyme beta lactamase in gram-negative bacteria cephalosporin penetrates the outer membrane through the pore and channel and binds to the pvp blocking its activity which leads to the failure of cross-linking
Between the 2 glycoprotein polymers which stops the pedicle lichen synthesis causing a damage to the peptidoglycan layer and consequently damage than the outer membrane therefore cephalosporin has a bactericidal effect on gram-negative bacteria however some gram-negative bacteria can release the enzyme beta lactam anaise in its periplasmic space this enzyme binds
To the beta-lactam ring of cephalosporin and breaks the ring this consequently impairs the ability of cephalosporin to bind and block the pvp and thus losing its bactericidal effect clove onic acid can be added with cephalosporin in gram-negative bacteria clove onic as it penetrates the outer membrane through the pouring channel clove onok as it contains a beta
Lactone ring and has a high affinity for binding to the beta lactamase enzyme this allows cephalosporin to bind and block the activity of pvp leading to a firing of the cross-linking between the two clock a peptide polymers stopping the peptic like and synthesis causing a damage to the pedicle i can layer and consequently damage to the outer membrane therefore
Cephalosporin with clonic acid has a bactericidal effect on gram-negative bacteria that can release begins on beta lactamase
Transcribed from video
Cephalosporin: Mechanism of Action By Dr Matt \u0026 Dr Mike
