Calcium
Hello ladies and gentlemen welcome back to our ongoing series of lectures on anesthesiology today we are going to talk about calcium we discuss in this lecture mechanism of action indications pharmacokinetics usual dose common side effects serious side effects precautions if you are new on my channel please subscribe my channel and also follow me on instagram
So let’s go to start our lecture calcium first isolated by humphrey davy in 1808 it is classified as a calcium salt most widely used as calcium gluconate calcium gluconate introduced in 1920 no dose adjustment required in geriatric hepatic or renal impairment patient always monitor ecg and serum calcium level every four hours in intravenous calcium therapy
Patients calcium is prime drug in cardiac arrest and cardiotoxicity due to hyperkalemia or hypermagnesemia mechanism of action calcium plays a central role in a large number of physiological action that are essential for life which includes cardiac automaticity excitation contraction coupling in myocardial smooth and skeletal muscle blood coagulation neuronal
Conduction synaptic transmission hormone secretion and mitotic division indication hypokalemia hydrofluoric acid burns hyperkalemia hypermagnesemia beta blocker toxicity calcium channel blockers toxicity allergic condition spider bites pharmacokinetics atomic number 20 formula c12h molar mass 430.373 grams mole roots oral intravenous topical usual dose
Adults 500 milligrams to 2 grams children 200 to 500 milligrams infants not than 200 milligrams common side effects warmth nausea vomiting heavy feeling bradycardia chalky taste in your mouth upset stomach gas constipation serious side effects little or no urination irregular heartbeats lightheadedness feeling tired precautions calcium infusion can promote
Vasoconstriction and ischemia in any of the vital organs and seen high in patients with low cardiac output aggressive calcium replacement can promote intracellular calcium overload which can produce lethal cell injury particularly in patient circulatory shock so avoid it always give calcium solution in large or central vein with small intracath due to hyperosomality
Of calcium solution contraindications digitalized patients ventricular fibrillation and hypercalcemia anesthesia with dr t please subscribe to my channel for more videos thanks
Transcribed from video
Calcium | Calcium Gluconate | Mechanism of Action By DOCTOR T