Salicylate Drugs
Hi my name is lindsay tosa i’m an expectation chef student at auburn university and my drug class today i’ll be discussing is salicylates so in this drug class we have aspirin we have a few other medications that fall under generic dose of aspirin they add my ass in here and i’m going to be teaching you a little bit more about the side effects pros and cons about
Aspirin so non solicited salicylates either also discussed under aspirin these are a type of in said it’s a subclass again said that block certain natural substances in your body so we decrease pain and decrease inflammation what else is act action of aspirin it interferes with a blocking blocking clotting actions and prevents any sort of clots therapeutic effects
So mainly its daily pain inflammation fever and excessive blood clotting disorders also prevents angina chest pain headaches prophylaxis of mi strokes and tas pharmacodynamic so we use to prevent heart attacks and any sort of blood clotting or decreasing any sort of blood clots and patients there also like we said used for decreasing pain inflammation swelling
And lowering temperatures pharmacokinetics absorption so rapidly from the stomach to the intestine it’s distributed when aspirin is transformed into salicylate it is an active metabolite responsible for most anti-inflammatory effects metabolism is short half-life of 15-20 minutes may only metabolize analyzer the liver and excreted through the urine so form of our
Therapeutic um exit so precautions we want to teach our patients the use of aspirin with petrova’s or any other team whose increase hassle estate in them so we want to make sure you’re not taking too much of pepto with your active daily aspirin if that’s the case contraindications we don’t want to use these five to seven days before a procedure position it’s a book
Thinner so it can cause bleeding unless your doctor recommends you taking it also patients with asthma or nasal polyps that could be hypersensitive to solicit late patients that is not recommended and kidney liver failure bullet eating disorders people that are pregnant present pregnant or breastfeeding because it does cross that blood bank brain barrier and um
Against drug reaction so common side effects will have abdominal cramps pain indigestion nausea and fever swelling of the feet or rare side effects extreme stomach pain bloody tart stools coffee ground emesis chest tightness and irregular heartbeats so it’s like poison we will talk about over here but drug interactions we want to know or heparins hang on advil
Which is also an in said there are any other dietary supplements evening primrose fatty acids skin kind of stuff like that so rational drug selection is low cost you can get over the counter and trap it acting but it’s important to discuss with your doctors make sure if you need to be on it so we want to monitor salicylate toxicity overdose so these are including
Vomiting tinnitus confusion hyperthermia metabolic acidosis rhabdomyolysis in multiple organ failure so in these patients make sure you’re also monitoring the use of wintergreen oil and kids if you drink less than five milliliters this will be toxic also with the peptone patients with autoimmune disorders or arthritis they’re taking more of this act so we want to
Make sure that we’re giving them education on toxicity there’s no antidote you would give activated charcoal or possibly human dialysis if toxicity is severe education don’t want to take longer than 10 days if you’re using if you’re paying or longer than three days if you’re using it for fever something else might be going on so you want to talk to your physician
About this administration you would usually take it with a 8 ounce glass of water and don’t lie down for 10 minutes the most common does is 81 milligrams daily so it main takeaways what our salicylates and where they used to treat pain inflammation fever prevent excessive blood clotting whether they do in their accident block certain receptors they decrease swelling
And pain when do you want to prescribe so patients that have a history of heart attack stroke or ti we want to put them on a daily aspirin not recommended in our kidney liver the units on our patients and you will also teach our patients with arthritis what to teach our patients um you want to make sure that if they had a stroke heart attack or ti a that they take
Their aspirin every day because this can lead to a life-threatening heart attack if stopped all right i think i covered it all thanks for tuning in
Transcribed from video
Auburn Pharmacology Project: Drug class:Salicylates By lindsey tullis
