Antiarythmic Drugs
In this lecture we are going to study about the class 1c sodium channel blockers in the lecture before we have already discussed the class 1b class 1c sodium chain and blockers the mechanism the mechanism causing the cardiac arrhythmia and the normal cardiac action potential you’ve already discussed such kind of topics in the lecture before so in order to
Register these drugs you must watch the lectures so talking about the class 1 c sodium chain and blockers so the important properties generally features are that it has a maximum sodium chain or block or resistivity and this will cause the mark depression in the past zero depolarization and thus it will cause the mark depression in the conduction velocity as you’ve
Already discussed that conduction will last you due to pressure dipolarization and this mostly occurs in the tissue like parkanji fibers bundle up his and the accessory pathways and these are the main pathways for the generation of what for the generation of eritrea due to impulse connections so blocking these pathways in pathways impulse conduction okay is so
Marked that it can decrease the conduction velocity even at the muscles which are at rest which are at rest so this can lead to the its pro arrhythmic activity the second important point is that it has no very little effect and the effective refractory period it has no relative effect on the hypocritical attribute so are drugs the first drugs which is class 1
C sodium channel blockers which is called the plicanoid or the e can either sector the canine or ek9 ekinite is another drug but belong to this drugs group important point that it is the beta blocking activity and this will cause the negative ionotropic effect on the heart and the seed is contraindicated in the congestive heart believer it is contraindicated
In the congestive heart flavor it has a much more beta blocking activity it is mostly used in the condition like atrial bladder improvisation in the bypass bypass trek medicated take arrhythmia and the ventricular take arrhythmia it has a adverse effect like uh blood vision although it is better to tolerate it like it can cause the blood vision gi side effects
Like nausea vomiting and diarrhea and the important point is that it is pro-arrhythmic in this patient which have already a heart disease it is pro arrhythmic in the patient which is already have a heart disease and it has proven through the research which is called cause which is called which is called caste and it stands for the cardiac arrhythmia suppression
Test research information related so it is contraindicated it must wash very very pro arithmetic in depression with the underlying heart disease so it is not used due to this it is not used now the second drug is the proper phenomenon it has the same properties except that it has a very mild beta blocking activity and it caused the adverse effect like dizziness
Light headedness and atixia it also called metallic taste in the mouth and the important adverse effect is called lips like facial rash which is xantinitis fostolosis exam tomatoes osteologist it is also pro arithmetic is the black and i and its uses are the same as we have discussed in the naki9
Transcribed from video
Antiarythmic Drugs|Class 1C Sodium Channel|Blockers|Profapenone|Flecainide By Medicoscool
