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Alzheimers, Myasthenia Gravis, Parkinsons Medications – Pharmacology – Nervous |@Level Up RN

Posted on October 26, 2022 By
Health

In this video, Cathy covers medications used to treat the symptoms of Alzheimer’s disease (donepezil), Myasthenia Gravis (neostigmine, pyridostigmine), and Parkinson’s disease (levodopa/carbidopa, bromocriptine, benztropine).

Continue talking about important nervous   system medications. if you are following along  with cards, i’m on card 82. we’ll be talking   about medications that are used in parkinson’s,  myasthenia gravis, as well as alzheimer’s disease.  is sometimes used in patients who have  donepezil helps to increase acetylcholine  by inhibiting

The action of cholinesterase,   which is an enzyme that breaks down acetylcholine,  their cognition, and their ability to perform  their activities of daily living, or their adls.  keep in mind that this medication does not cure  alzheimer’s disease. it is really just to help   side effects can include  headache, diarrhea, and

Nausea.  and then my little trick for remembering this   medication, if you look at the word, donepezil,  you have that don, and then you’ve got pez. so   alright. let’s now talk about some cholinergic  medications that are used to treat myasthenia   gravis. medications that fall within this class  include neostigmine as well

As pyridostigmine.  these medications can help improve the strength  and mobility in patients who have myasthenia   gravis. they are also used to help reverse the  effects of neuromuscular blocking agents as well.  acetylcholine at the receptor sites by inhibiting   so my weirdo way of remembering these medications  is if you

Look at the two drug names, they both   contain stig. stig is a famous racecar driver  in the show top gear. so stig, he’s coming in   to save the day. he pulls up with his race car,  and he’s like . and he blocks   cholinesterase. and by blocking cholinesterase, he  prevents the breakdown of acetylcholine and helps  

With anticholinergic medications, you get a lot of  drying side effects, right? can’t see, can’t pee,   can’t spit, can’t poop, right? with cholinergic  medications, everything’s going to be very,   very moist, so you’re going to get side effects  such as increased salivation, diarrhea, nausea   and vomiting, sweating, as well as

Bradycardia so  just think of all those moist things and that will   another cholinergic medication that’s important   myasthenia gravis and to make sure that’s  what we’re dealing with, myasthenia gravis,   so if we give edrophonium to a  patient who we suspect may have   if we give edrophonium to a patient and they

Get  worse, then that means they were probably having   a cholinergic crisis instead. and then we need  to administer the antidote which is atropine,   medications that are used to treat parkinson’s  patients have too little dopamine and too much  acetylcholine. so treatment is usually centered   around trying to bring up

These dopamine levels  and decrease the amount of acetylcholine onboard.  so our first class of medication that we’re going  to cover are dopamine agonists. medications that   and carbidopa, which are used together,   are used to help decrease symptoms in parkinson’s  disease including tremors and muscle rigidity.  there are many,

Many side effects with these  medications. so side effects can include nausea   and vomiting, drowsiness, orthostatic hypotension,  darkening of urine and sweat, possible psychosis,   keep in mind that consuming high protein meals   should actually consume a low protein diet to  ensure adequate absorption of this medication. 

That carbidopa and levodopa drive in their   disease) to increase levels of dopamine.   so both of those words in that -dopa, which will  help you to remember that both of those things   anticholinergic medication that is used to  treat parkinson’s disease, which is benztropine.  benztropine helps to bring down those levels of 

Acetylcholine which helps to improve symptoms   because it is an anticholinergic medication,   it will have those drying effects. and my mnemonic  again for how to remember those anticholinergic   so you can expect side effects with benztropine  urinary retention, and constipation. side effects, you should advise your patient to 

Chew gum or suck on hard candy for that dry mouth,   increase their intake of fluids and fiber   pick it up with more important nervous  if you’ve found value in these videos, be sure  to like and subscribe to us here at level up rn!

Transcribed from video
Alzheimer's, Myasthenia Gravis, Parkinson's Medications – Pharmacology – Nervous |@Level Up RN By Level Up RN

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