All About Prokinetics for SIBO// If you keep having SIBO relapse, you will want to learn about prokinetic medications. Using prokinetics for SIBO helps prevent SIBO relapse, and improve your IBS symptoms and small intestinal bacterial overgrowth. In this video, I explain what prokinetics are, how to use prokinetics to prevent SIBO relapse, and also share about natural prokinetics.
Today i’m going to talk about using prokinetics for sibo and how to use them properly to prevent welcome back. i’m really glad to see you again, and if you’re new here, welcome for the first certified functional nutrition health, gut detective. for weekly videos on how to find your personalized plan for ibs and sibo
Resolution, please consider subscribing and be sure to hit what if i told you that there was a simple add-on to your sibo treatment plan that dramatically reduced the likelihood of relapse after sibo treatment? i’m talking about prokinetics, which are medications or supplements that encourage as an expert
In ibs and sibo gut health, people who are really struggling but haven’t been told about prokinetics by their doctors or aren’t aware of them. in this video, i want to explain what prokinetics are and how to use them so you can put them to work for you all right. to start things off, let’s first talk about what
Prokinetics are. they’re basically medications or supplements like i mentioned, that help encourage material to move through your gut at a good speed so that bacterial overgrowth can’t build up. now as i’ve mentioned in several other videos, sibo is primarily a motility disorder, meaning that the slowdown of movement
Of material through your small intestine is what leads to the bacterial overgrowth called sibo. even if you remove the bacteria with antimicrobial herbs or antibiotics, if you don’t tend to this motility problem, the sibo is likely to just regrow and come back right after treatment or shortly after treatment. so
Prokinetics are medications that help prevent that regrowth by just supporting that movement of material through your intestine. there are several different types of prokinetic medications that have different mechanisms of action. the first type are called cholinergic agonists, which sounds really complicated, the
Gut. these types of prokinetics typically aren’t used for ibs, they have other purposes. dopamine antagonists, meaning that they bind of this type of medication is called reglan, and reglan is also not typically used for ibs or sibo purposes. i do think that low-dose naltrexone and in some circles, low-dose naltrexone
Has been recommended as a prokinetic for use after sibo treatment. but the effect of the low-dose naltrexone is pretty small and minimal compared to some of the other medications available for the third type of prokinetics are called serotonergic agonists. so again, an agonist is something that promotes
Something else. this medication promotes the action of serotonin in the gut. and we know that something like 70 to 80% of the serotonin in our bodies is produced in our gut, and there are tons of serotonin receptors there. these serotonin receptors have something to do with our gut motility. they are involved in that
Process. so one medication that used to be used for this was called tegaserod, and i’m not sure if that’s how you pronounce it. it’s no longer used for ibs purposes because it tended to show some side effects on the heart. came out in the last couple of years called with fairly minimal side effects and has a very
Targeted action on the small intestine, and so is a really useful prokinetic for use after sibo treatment. use of prucalopride usually helps and the fourth category of prokinetic medications antibiotics that have some sort of prokinetic effect, and the most commonly used one for the purposes of post sibo treatment
Is called low-dose this context. one is called motilpro, which is primarily a ginger supplement. and the it’s a liquid herbal supplement that again, encourages this small intestinal motility and cleaning. these herbal supplements tend to have a less specific mechanism and effect than the medications, and they
May need higher doses to achieve the same level of prokinetic activity than the medications, but they are also options, now, i do want to take a minute to note that laxatives are not the same as prokinetics. laxatives are more directly targeted to the colon of liquid or water that’s hanging out in the
That help evacuate stool. these supplements are medications will produce bowel movements, but they don’t have the same direct effect on the small intestine to move things through and encourage those natural cleaning waves in the like senna or medications like miralax are all right, so how do you use prokinetics
It’s recommended that you begin them immediately after finishing your sibo treatment, whether neomycin or herbal antimicrobials like allicin and oregano oil or the elemental diet. they’re typically prescribed to use at bedtime because our longest fast during the 24 hour period is our overnight fast while we’re sleeping. and
This is the time of day when our natural and normal small intestine cleaning waves are the strongest. and so using the medication at night helps really enhance and encourage that natural cleaning wave sometimes it can take a little tinkering with the medication dose to get just the right amount so that you have
A good therapeutic effect, and you don’t also have unwanted side effects like diarrhea or loose stools the next day. you can discuss with your doctor the appropriateness of titrating the medication and strategies for like, “how much should i try at first and how can i work up to the minimum needed therapeutic dose?”
Now, a lot of people will wonder if they should still use prokinetics if they already trend towards diarrhea, and the answer is usually yes. again just like i mentioned with the laxatives, the encouragement of these natural cleaning waves in the small intestine is really distinct and different from the process that can
Cause diarrhea in the large intestine. however that being said, sometimes prokinetics will aggravate loose stools and trigger diarrhea. this is something you have another question a lot of people have is, how long should i continue using the prokinetics once i’ve started them? you should definitely consult
With your doctor to get a clear answer for this for your unique situation. but usually what i encourage people to do is to think about trialing the medication or supplement for about two months. then you can titrate your prokinetic down and see if you maintain your symptom relief. if not, maintaining symptoms, then
Congratulations, but it is important to know that people who use prokinetics after sibo treatment tend to have treatment than those who do not. on average, it lasts more like six months versus one month. the name of the game is using this consistently for a little while to just encourage that natural cleaning wave
Action. and there’s some evidence to suggest that supporting it can help rebuild natural function if that natural function has broken down for one reason or another. so you just want to use it and give your body a chance you’re still having success with that or not, do you have a question about prokinetics
If so, leave me a comment down below this an overview of how prokinetics can help reduce the amount of relapse episodes you’re having with your sibo. and i want to let you know that if you’re someone who’s been unsure how to navigate your sibo treatment for success, this is exactly the kind of thing i help my clients
With inside my online program called the calm digestion method. i want to let you know that if you’ve been unsure treatment, or how recurring sibo that won’t go away, that this is exactly what the signature if you want to get your hands on that strategy and see if it might be able to help you, grab a free
Copy of that roadmap by going to confluencenutrition.com/roadmap and i will leave a all right, let me know if this video was helpful comment. you might want to check out this video called frequently asked questions about sibo next on that. it includes some really important details. so hope that helps you out,
And i look forward to seeing you all next time.
Transcribed from video
All About Prokinetics for SIBO (PREVENT SIBO RELAPSE) By Confluence Nutrition