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In today’s video we’ll learn the classification of sympathomimetic and sympatholytic agents this is an overview sympathomimetics also known as adrenergic agonist sympatholytics or adrenergic antagonists simpesolytics are again classified as alpha blockers and beta blockers first one sympathomimetic agents or adrenergic agonists these agents activate the adrenergic
Receptors they are mainly classified into three direct acting indirect acting agents and agents with mixed action the direct acting agents act on alpha and beta receptors or both the direct acting adrenergic agonists are norepinephrine epinephrine phenylephrine dopamine methyl dopa clonidine naphazoline oxymetazoline xylomethazoline dobutamine isoproterenol
Salbutamol biotolterol next the indirect acting agonists hydroxyamphetamine pseudoephedrine the agents with mixed action are ephedrine meteoraminol the direct acting agents act on alpha and beta receptors or both the indirect acting agents act on adrenergic neuron to release noradrenaline the mixed acting agents possess both direct and indirect actions so this
Is the classification of sympathomimetic drugs or adrenergic agonists sympatholytic drugs are agents that block the adrenergic receptors we have alpha blockers and beta blockers alpha blockers are mainly divided into non-equilibrium type and equilibrium type the non-equilibrium type is beta halo alkylamine example phenoxy benzamine the equilibrium type is further
Subdivided into non-selective alpha one selective and alpha two selective alpha one selective is divided into four classes ergot alkaloids hydrogenated goat alkaloids imidazolines and miscellaneous types the ergot alkaloids are ergotamine ergotoxin the hydrogenated ergotyleglots are dihydroergotimine or dhe and dihydroergotoxin imidazolins are phentolamine
Tolazoline miscellaneous chloropromazine class of equilibrium type is alpha one selective prazosine sin doxazosin alphosin tamsulosin and the last one is alpha to selective yohimbine so that is the classification of alpha blockers next is the beta adrenergic blockers these drugs inhibit adrenergic responses mediated through the beta receptors mainly classified
Into non-selective and cardio selective in the non-selective we can see isa which means intrinsic sympathomimetic activity it’s classified into three types the non-selective without isa with isa and with alpha blocking property without isa example propanol satellite timolol with isa pindalol with alpha blocking property labitylol and carbidylol the next important
Class of beta blockers are cardioselective metaprolol ethanol acetylol bisoprolol asmulol betaxolol cellyprolol nebulal are all the examples you
Transcribed from video
Adrenergic agonists(Sympathomimetics) & Adrenergic antagonists(Sympatholytics) Classification By Study Pharma
