Adderall is a combination of dextroamphetamine and levoamphetamine that is commonly prescribed for ADHD. It effectively combats ADHD in many people, and in healthy users, it can provide an acute cognitive boost.
Adderall is a combination of dextro and levo and feta mean that’s widely used to treat adhd in to a lesser extent narcolepsy it effectively combat adhd in many people and it can provide cognitive enhancement at least in the short term for healthy individuals because of its stimulant and cognitive enhancing effects adderall is often used by college students and
Workers the drug safety differs depending on the dose so therapeutic amounts used for adhd may be different than chronic high doses used for other reasons i won’t fully cover the specific effect adderall has on adhd in this video since it’s a large topic that deserves a video of its own among the positive effects of adderall are greater alertness stimulation
Greater sociability mood lifts euphoria increased focus cognitive enhancement improved physical performance in increased motivation the negative effects can include increased heart rate increased blood pressure reduced appetite paranoia fever anxiety aggressiveness insomnia diarrhea irregular heartbeat and increased temperature very high acute and chronic doses
Are associated with psychosis and convulsions at high recreational amounts adderall can result in jaw clenching difficulty remaining still a general uncomfortable feeling and a negative effect on cognitive performance the effects are to some extent different between users with adhd in those without adhd adhd users can still get stimulant effects especially at
Higher doses but at normal medical amounts they receive a largely non-recreational boost in focus alertness and motivation adderall doesn’t really calm these individuals in terms of providing a sedative effect but it does reduce hyperactivity and task switching two of the core issues with adhd without delving into detail adderall can greatly improve adhd symptoms
In many children and adults it doesn’t work for everyone but when it does work it can address the symptoms and may even begin to normalize brain activity and structure studies reliably connect the medical use of stimulants like adderall to positive changes in brain activity and structure those changes push adhd affected individuals closer to what you’d see with
Normal individuals adderall may have negative behavioral effects but in terms of brain health it doesn’t appear to damage the developing brain in medical settings orally it lasts for three to five hours and begins working in ten to thirty minutes intranasally it lasts for two to four hours and begins working in less than 10 minutes adderall is made up of four
Amphetamine salts amphetamine aspartate monohydrate amphetamine sulfate dextroamphetamine sulfate and dextroamphetamine sakura together this provides 75% dextroamphetamine and 25% level and feta mean the drug mainly works by raising dopamine and norepinephrine activity amphetamine is a full agonist at trace aiming associated receptor 1 and vesicular monoamine
Transporter 2 tarr wan is a key modulator of mono amines dextroamphetamine has greater activity at tar 1 meaning it provides greater cns stimulation level and feta mean has some greater nor pinet activity and as such can provide more arousal at low doses as the dose increases dextroamphetamine becomes responsible for much of the stimulation and it also provides
More behavioral effects both substances impact serotonin but not to a particularly significant degree adderall causes the dopamine transporter to no longer reuptake dopamine on top of that it reverses the flow allowing more cytoplasmic dopamine to enter the synapse adderal also inhibits the storage and reverses the flow of dopamine in neuronal vesicles meaning
More accumulates in the cytoplasm amphetamine was synthesized by lazaro delano a romanian chemist in 1887 in the 1930s it entered the market as benzedrine which was used to combat congestion and it was already being used for adhd by the late 1930s in 1996 richwood pharmaceuticals introduced the adderall brand which was initially only offered as an instant release
Large amounts of adderall are now diverted from medical use and used for recreational or performance-enhancing reasons it’s also clear that people may have admiral prescriptions without a legitimate case of adhd depending on the college up to 25 or 30 percent of students have used adderall or other stimulants for non-medical reasons orally a light dose is 5 to 15
Milligrams of common dose is 15 to 40 milligrams and a strong dose is 40 to 75 milligrams intranasally a light dose is 5 to 10 milligrams a common dose is 10 to 30 milligrams and a strong dose is 30 to 50 milligrams the drug is scheduled to in the us and it’s also controlled in the uk new zealand canada australia and many other countries at any regularly used dose
There is cardiovascular stress in the form of increased heart rate and blood pressure this can result in notable tachycardia and possibly palpitations at high doses this is mainly a concern for compromised individuals when the drug is used at high doses or when it’s combined with other drugs or exercise in those scenarios a heart attack or hypertensive crisis is
Possible neurotoxicity is a common concern but there’s not much evidence to support major concerns about amphetamine induced neurotoxicity especially at medical doses methamphetamine is known to cause damage at high doses and the concern appears smaller with em fed amin dextro and levo and feta mean don’t seem to be connected to neurotoxicity at therapeutic doses
Even with long-term use but the concern isn’t 0 percent when adderall is used at very high doses or at high doses chronically so you must be wise with your use accu overdoses do occur and death featuring convulsions in coma is possible but overdoses rarely lead to death a moderate overdose comes with rapid breathing abnormal heartbeat agitation confusion tremor
Elevated body temperature urinary retention and muscle pain a severe overdose may feature psychosis muscle breakdown kidney failure convulsions circulatory collapse cerebral hemorrhage and a very high body temperature tolerance – adderall builds quickly and withdrawal can be uncomfortable though not fatal the core effects of withdrawal exist for around a week a
Major drop in energy and a rise in depressive symptoms is common over all the withdrawal can include anxiety fatigue depression increased appetite lack of motivation mood swings and both sleepiness and sleeplessness some combinations that can be particularly dangerous include mao is tramadol psychedelics tricyclic antidepressants and other stimulants if you have
Any questions about adroll feel free to leave them in the comments section support on patreon is greatly appreciated so if you’d like to contribute you can head to patreon.com / the drug classroom you can also contribute through youtube paypal or bitcoin using the addresses and links in the description you can connect with me on twitter at seth a fitzgerald and by
Email at seth at the drug classroom comm more information and links to references can be found on the tdc website using the link below you
Transcribed from video
Adderall: What You Need To Know By The Drug Classroom