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Acetaminophen formula acetaminophen also known as paracetamol or alba is a medication used as anti-inflammatory and antipyretic it is on the world health organization list of essential medicines needed in any health system formula and structure the acetaminophen has the pack name and four hydroxyl phenylacetone in its chemical formula a c8 h 9 note 2 and it’s
Extended formula is hawk 6h for night 3 dot its molar mass is 151 point one six five grams bill minus one the molecule is formed by an aromatic phenyl ring which has two substituents in position para 1 comma 4 the first substituent is an amide group asset amide and the second is a hydroxy group o the molecule is planar with 7 carbon atoms with sp2 hybridization
Its chemical structure can be written as below in the comment ations used for organic molecules curren acetaminophen is not found in nature similar to aspirin it was synthesized by the first time in 1877 by harman northrup morse however it was not used as antipyretic until 1893 after researchers from germany found the paris tumult in the urine of patients which
Were being treated with faison today it is known the paris malt is part of the metabolism of a gradation of aysen preparation acetaminophen can be synthesized by the isetta latian of foraminal phenol when treated with the c2 kassadin acetic anhydride at high temperatures it can also be prepared by the treatment of acetic anhydride in pyridine or with acetyl chloride
And pyridine and will unl all reactions are performed at 70 degrees celsius the first step of this process is the obtention of foraminal phenol through the reduction of four-night result in presence of sodium borohydride physical properties acetaminophen is a colorless to white crystalline solid it is odorless and it has a bitter taste acetaminophen density is one
Point two nine three grams milliliter minus one it’s melting and boiling points are 168 degrees celsius and 420 degrees celsius respectively it is soluble in boiling water ethanol methanol dimethyl formamide ethylene dichloride ethyl ether and acetone it is insoluble in ether cold water and benzene chemical properties acetaminophen mechanism of action is thought
As similar to aspirin through the inhibition of enzyme cyclic sahjhan ace causing the suppression of prostaglandin production moreover it is also inhibited nitric oxide root to increase the pain threshold the paris thermal molecule is extremely reactive in the body do its chemical structure that has two activators substituents owen copper which results in very
Reactive molecule toward aromatic substitution uses acetaminophen is largely used to reduce fever and pain and people including children moreover it is also used in the treatment of arthritis it is used as raw material and intermediate in the production of other medicines acetaminophen is mostly used through the oral consumption fex safety hazards at the same way
That other medicines acetaminophen long-term consumption can be dangerous to health especially to liver it does not cause gastric irritation as the aspirin it may cause irritation to eyes
Transcribed from video
Acetaminophen – Physical,Chemical Properties By Reo Kel
