Overview of ACEI: review action, uses, adverse effects, contraindications as well as nursing implications.
Hello and welcome to nursing bites by nadia let’s switch gears a little bit and do some pharmacology let me give you a brief overview of ace inhibitors today examples of ace inhibitors are bonazeparal and allopro lisinoprol rabbit pearl facinapril captain pro basically anything that ends with a pearl you can pre you can be pretty sure that it’s an ace inhibitor
They’re well absorbed orally produce an effect about one to have one and a half hours after oral administration the drug is excreted in the urine in addition to hypertension it’s also indicated for treatment of proteinuria in patients with diabetes as well as renal disease ace inhibitors block the enzyme that normally converts angiotensin 1 to the potent vasoconstrictor
Androtensin-2 by blocking production of angiotensin ii the ace inhibitors decrease vasoconstriction thus producing vasodilating effect and decrease aldosterone production and by doing so reduce retention of sodium and water in addition to that ace inhibitors also inhibit the breakdown of bradykinin prolonging its vasodilating effects ace inhibitors are used to treat
Heart failure and hypertension they may be effective as monotherapy in caucasian patients or in combination with the diuretic and african american patients ace inhibitors are also recommended for patients with hypertension and diabetes and subsequent kidney damage and albuminuria ace inhibitors improve post mi survival when added to the standard therapy of aspirin
Beta blocker and thrombolytic usually ace inhibitors are well tolerated they have low incidence of serious adverse effects such as neutropenia agranulocytosis proteinuria glomerulonephritis and andrew edema it is very important to know what andrew edema is angioedema is a sudden deep swelling or wealth under skin particularly around eyes and lips such occurrence
Is an emergency and has to be reported to the treating physician immediately expected side effects of ias inhibitors often which often pops up in nclex questions is persistent dry cough it develops in significant number of patients of note the cough can develop years after initiating the drug or after several first doses hyperkalemia is another side effect that
May develop in patients with diabetes or renal impairment or those who are taking nsaids such as ibuprofen or in patients who take potassium supplements please note that patients who use salt substitutes which are mainly comprised of potassium also have increased risk of hyperkalemia use of ace inhibitors is prohibited in pregnancy due to injury or even death to
A developing fetus additional contraindications include allergy to medication or prior occurrence of android edema nursing implications you may crush the tablet for patients who cannot swallow monitor the blood pressure before and after administration to assess for effect assess for adverse effects such as acute hypotension upon initiation of drug therapy check
Serum potassium levels prior to administration if the patient’s potassium level is already high please make sure to consult a pharmacist or physician prior to administration this concludes today’s brief overview of ace inhibitors i’ll speak about other hypertension um antihypertensive medications in the next videos if you’d like to see something in particular please comment below
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ACE inhibitors – quick overview By N for Nurse
