🩹 Dermatology Course:
Welcome back in this video i’ll teach you everything that you need to know about hiv treatment keep in mind before starting any treatment the patient must be tested for resistance the newly updated guidelines indicates the following once resistance has been rolled out start the patient on a combination of three medications two from the class in rti and one from
The class integrase inhibitors if this treatment fails to reduce the viral load in six months to undetectable levels go to the second line which is adding either nnrtis or protease inhibitors or interior inhibitors in pregnancy things are a little bit different if the patient has already been diagnosed with hiv and is already taking treatment continue the
Same treatment during pregnancy but if she’s just been diagnosed with hiv during pregnancy start the first line which is two in rti’s plus one integrase inhibitor immediately without testing for sensitivity during labor perform cesarean section if the viral load is more than one thousand or the cd count is less than two hundred otherwise deliver vaginally all
Newborns of hiv mothers must be given zadovudine intrapartum which means during delivery and for six weeks after delivery and the newer born should be tested for hiv using pcr only because the routinely done elisa will be false positive due to the maternal antibodies here are the most common side effects that you’ll likely see in the exam zidovodine is
Known to cause anemia stavodine and didanosine are known to cause pancreatitis and neuropathy a behavior causes steven johnson syndrome in patients with hla b5 mutation protease inhibitors are known to cause diabetes and dyslipidemia and in the never causes renal stones tino fever has two forms diesoproxyl which causes osteoporosis and renal tubular acidosis
And alafinamide which is trapped within the cd4 cells and does not cause any side effects sometimes we can use two medications that we can combine to increase their levels for example lvt gravier is combined with kobesy stat to increase its levels darunavir and athazanovir are combined with ritunavir to increase their levels alright guys that’s all i have thank
You so much for watching and hopefully this helps
Transcribed from video
Abacavir, Didanosine, and Emtricitabine – HIV Medications (Antiretroviral Therapy) By USMLE pass